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HPV IN IMMUNOSUPPRESSED PATIENTS

HPV IN IMMUNOSUPPRESSED PATIENTS

HPV IN IMMUNOSUPPRESSED PATIENTS HPV treatmentHPV MEDICAL CENTER and HPV MEDICAL GROUP HPV MEDICAL GROUP has been created to prevent, to diagnose and treat HPV before it develops into cancer. For this purpose, we use DNA detection techniques (PCR and hybrid-capture) which allow us to make a diagnosis of the virus in its early stages of infection, also called “latent stage”. At the same time, these techniques let us know if the virus is benign or related to cancer being able to establish the risk of the infection.


Most of our members have been trained in our country and abroad and were awarded for their research projects and medical journals in International Medical Congresses.

One of our departments in our center is oriented to research in Clinical Pharmacology, working for the pharmaceutical industry with national and international laboratories, contributing to the development of new drugs. Part of our team has worked in the production of pharmaceutical drugs since the 60’s as well as in the development of new diagnostic techniques currently applied becoming pioneers in some areas of medicine. As a result of our work, we have successfully treated thousands of patients to date. We are continuously pushing ourselves to find new cures for diseases taking them as a challenge.


We have been working for more than three years in new therapeutic approaches to treat Human Papillomavirus in its different stages of infection.

These techniques were designed after several years of using classic therapeutic procedures such as the use of trichloroacetic acid, podophyllin, interferons, podophyllotoxin, electrocautery, leep, others, that produce regular results and suffering for the patients.

The main goal of our medical team is the treatment of human papillomavirus in clinical phase, and early stages.

Early detection and treatment of human papillomavirus allowed us to perform new therapeutic approaches that will be communicated in medical congresses and published shortly.


HPV Medical Center main goal:

    * Report about the Human Papillomavirus (HPV).
    * Report about  the importance of early diagnosis of human papillomavirus (HPV).
    * Report about the causal relation between HPV and Cervical Cancer.  Causal relation between HPV and anus, penis, vaginal, vulvar, mouth and other types of cancer.
    * Prevention of Cervical Cancer and others.
    * Importance of early diagnosis through DNA techniques, Pap smear, colposcopy, microcolpohysteroscopy.
    * HPV in men, penis cancer and HPV.
    * HPV in immunocompromised patients.
    * DNA Test for early diagnosis.  Protein Chain Reaction (PCR) and Hybrid Capture.
    * Prevention of  cervix, vagina, vulvar, anus, penis, mouth and other cancers associated with HPV.
    * Preventive vaccines against HPV.
    * Diagnosis and treatment of HPV.
    * Approach to partner with HPV.
    * HPV in children and new born.
    * Treatment of HPV in early stages.
    * Treatment of HPV in advanced stages.
    * New HPV treatments. Investigation area.


Human Papilloma Virus or HPV is a DNA (deoxyribonucleic acid) virus.
HPV virus carries genetic information. Molecular biology techniques deciphered the genetic code of most HPV virus and its relation with aggressiveness and human body locations of the infections.

DNA is like a program that every cell of the human body has. It contains all the information that give us our physical appearance, individual and unique characteristics. The same goes for Human Papilloma Virus (HPV).
More than 100 types of HPV have been discovered. They differ in their DNA which make HPV more or less aggressive, infect the body in different locations,  give them a causal relation with Cervical Cancer, other types of cancer, skin and mucosal epithelium diseases,  or simple genital warts.

HPV is a DNA virus that affects only humans.

H=Human.
P= Papilloma                                                                                         
V=Virus

Human Papilloma Virus or HPV virus belongs to the family of papovavirus. Papovavirus are divided in two genera, type A and type B. Type A papovavirus do not induce infections in other species than humans and can not be cultivate. Their only host are humans.
Type B papovavirus does not affect humans and can be cultivate. They are important as a laboratory model.
Human papilloma virus or HPV virus are characterized by having a small diameter. Viral particles are identical by the electron microscope view, they differ only in their DNA.  More than hundred types of HPV have been discovered and new types are being discovered continually.
Many of the subtypes found are related to infections in male and female genitalia.
HPV virus infections are related with the genesis or development of some carcinomas of the female genitals, penis, anus, mouth, cutaneous carcinomas associated or not with skin warts. Depending on the subtype, HPV is a cancer cause.  
HPV genital infection is considered a sexually transmitted disease. Other transmission routes are possible, also the spread of mother to child during birth.

Drs. Herald Zur Hausen research was the first to establish a relation between HPV and genital cancer.
HPV (Human Papillomavirus) infection can persist many years, but also it is possible a self-limiting process with HPV disappearance defeated  by the body's defenses.
HPV genital infection has three stages, a latent stages were HPV (Human Papillomavirus) can only be diagnosed by DNA techniques, a subclinical stage were HPV can be detected by DNA techniques and the use of  some instruments like camera,  colposcopy, etc. The third stage or clinical stage permits us to see HPV lesions by the naked eye.

The certain diagnose most be done by molecular biology.

Using molecular pathology techniques, the HPV test, unlike the Pap smear, allows us to have a precise diagnosis of the Human Papillomavirus. The Polymerase Chain Reaction (PCR) is a painless technique which involves the extraction of cellular material as it is done in a Pap smear but, unlike this, it has a sensitivity of 100% in the cervix. In other words, there is no possibility of false negatives if the extraction is correctly performed. This molecular biology technique, which we prefer and recommend, also gives us the possibility to find out which type of HPV the patient actually has. The importance of this lies in the fact that there are tumor viruses, in other words, viruses related to cancer such as: HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68, among others. There are other viruses related to benign warts which may result unsightly or contagious. This technique is also used in other genital areas such as the vagina, vulva, anus, penis or other parts of the body, which cannot be contagious, such as the mouth or areas of the skin near the genitals and different organs where the HPV infections are less frequent, on the other hand PCR lets us know if HPV vaccines will be preventive or not
Another currently used technique for detection of the HPV is the “hybrid-capture” test which gives us the possibility to obtain information about the human papillomaviruses connected to genital infection or cervix cancer as well as some benign viruses related to common warts. Unlike PCR, this technique does not report on the infectious type of viruses and it is only sensitive to the most frequently found viruses.
The “hybrid-capture” detects HPV viruses which are often found in the genitals. These one are classified in: Group I: 6, 11, 42, 43, 44, 53 and 54 called “low-risk” HPV types and which are not related to cancer; and Group II viruses, also called of “high-risk”: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68 related cancer.

HPV (Human Papillomavirus), can be considered a transforming agent thus called tumoral viruses.

Tumoral viruses such as some types of HPV cause the transformation of a normal into a cancerous cell. This is a result of HPV  ability to integrate its genetic information (HPV DNA) into the nuclear DNA of the host cell. Some HPV oncoproteins play an important role in this transformation.


  • HPV or Human Papillomavirus is a DNA virus. Each type of HPV has his one and individual genetic characteristics.
  • HPV or Human Papillomavirus is a virus that infects humans only.
  • HPV or human papillomavirus has many genetic variants and there are more than hundred types discovered by molecular pathology.
  • HPV or human papillomavirus can induce the transformation of a normal cell into a cancer cell.
  • HPV or Human Papillomavirus is fundamentally related to cervical, vagina, vulva, anus, penis, mouth, airways, skin and others types of cancer.
  • HPV or Human Papilloma Virus can be diagnosed early on by DNA techniques (PCR and Hybrid Capture).
  • HPV or Human Papilloma Virus also can be detected by Pap smear and Colposcopy but usually when it is already in advanced stages  


Consult us:
 

  • HPV in inmunosuppressed patiens
  • Improving the immunologic system

Consult us info@hpvmedicalcenter.com.ar